Clarke County is centrally located at the junction of Interstate 35 and U.S. Highways 34 and 69 and offers excellent transportation facilities. AMTRAK, Burlington Northern and Santa Fe Railroad, a modern airport, Jefferson Bus Lines, and the services of several truck lines make Clarke County a profitable business and industry location.
Osceola is only 45 miles from Des Moines International Airport, 145 miles from Kansas City, 130 miles from Omaha, 375 miles from Chicago and 300 miles from St. Louis. Woodburn is three miles east of Osceola on Highway 34 and one mile south. Murray is five miles west of Osceola on Highway 34.